To make something a priority means to give it importance and make it the most important thing to focus on. It means that you are placing a high value on something and making it your top priority to take care of or address. This phrase is often used in the context of setting goals, managing time or tasks, and making decisions. For example, if a person says "my family's well-being is my top priority," it means that their family's happiness and safety is the most important thing to them, and they will prioritize their actions accordingly.